Intracellular recording

3 Intracellular recording

Intracellular recording is the measurement of voltage or current across the membrane of a cell. It typically involves an electrode inserted in the cell and a reference electrode outside the cell. The electrodes are connected to an amplifier to measure the membrane potential, possibly in response to a current injected through the intracellular electrode (current clamp), or the current flowing th...

Intracellular recording in behaving animals.

Electrophysiological recordings from behaving animals provide an unparalleled view into the functional role of individual neurons. Intracellular approaches can be especially revealing as they provide information about a neuron's inputs and intrinsic cellular properties, which together determine its spiking output. Recent technical developments have made intracellular recording possible during a...

Necturus macubsus. II. Intracellular Recording

The recording of potentials from motoneurones with an intracellular electrode.

Multi-neuron intracellular recording in vivo via interacting autopatching robots

The activities of groups of neurons in a circuit or brain region are important for neuronal computations that contribute to behaviors and disease states. Traditional extracellular recordings have been powerful and scalable, but much less is known about the intracellular processes that lead to spiking activity. We present a robotic system, the multipatcher, capable of automatically obtaining bli...